Persistent asthma damages the cardiovascular system
Persistent asthma in adulthood she seems strengthened by it plaque build-up in the carotid arteries increase the risk of heart attack and stroke.
In a new study involving experts from University of Washington was investigated whether persistent asthma with storage plaques in the carotid artery (carotid arteries). The results are published in the Journal of the American Heart Association.
Data from the MESA study were evaluated
The team used data from Multi-Ethnic Study of Atherosclerosis (MESA), which included nearly 7,000 participants who started the course no cardiovascular disease had
In the current study, the researchers used data from 5,029 participants evaluated, who were on average 61 years old and at the beginning Risk factors for cardiovascular diseases were found. Carotid artery ultrasound data were also available for all participants, and 53 percent were female.
Participants were divided into three different categories: those with persistent asthma, intermittent asthma, and those without asthma. 109 participants they fell into the subgroup with persistent asthma, 388 participants into the subgroup with intermittent asthma and the remaining participants had no asthma.
Plaque measured in the carotid artery
At the beginning of the MESA study ultrasound examinations left and right carotid arteries to identify plaques in the carotid artery. The researchers explain that based on the number of plaques in the walls of both carotid arteries, the total value of the load was calculated.
In addition, blood levels of inflammatory biomarkers were also identified Interleukin-6 (IL-6) a C-reactive protein (CRP), the researchers add.
Dilated deposits of the carotid artery
Data analysis showed this 67 percent of participants with persistent asthma had plaques in the carotid artery, whereas this was the only case 49.5 percent of people with intermittent asthma and for 50.5 percent participants without asthma.
Additionally, people with persistent asthma who had plaques in the carotid artery had an average of two plaques, while the other groups had only one plaque on average.
The risk doubled for persistent asthma
After data were adjusted for possible confounding factors such as age, gender, weight, prescription drug use, or smoking, participants were assigned persistent asthma almost as compared to people without asthma twice as high The likelihood of plaque in their carotid arteries, according to the research team.
Additionally, participants with persistent asthma reported higher values inflammatory biomarkers on. “Participants with persistent asthma had elevated levels of inflammation in their blood even when their asthma was treated with medication, underscoring the inflammatory nature of asthma.” explains the author of the study Matthew C. Tattersall in a press release from the American Heart Association.
“This analysis tells us that the increased risk of carotid plaques in people with persistent asthma is likely influenced by multiple factors“, so Tattersall. Higher levels of inflammation are also known to lead to negative effects on the cardiovascular system.
One Chronic inflammation contribute to the creation plaques in the arteries which can break loose and cause a heart attack or stroke.
“Many doctors and patients do not realize that the inflammation in the airways in asthma can affect the arteries“, he emphasizes Tattersall. In more severe forms of asthma, treatment of cardiovascular risk factors by adjusting the so-called lifestyle and diet therefore, they will particularly contribute to prevention. (as)
Author and source information
This text meets the requirements of the medical literature, medical guidelines and current studies and has been reviewed by health professionals.
- Matthew C. Tattersall, Alison S. Dasiewicz, Robyn L. McClelland, Nizar N. Jarjour, Claudia E. Korcarz, et al.: Persistent asthma is associated with carotid plaque in MESA; in: Journal of the American Heart Association (veröffentlicht 23.11.2022), JAHA
- American Heart Association: Persistent asthma associated with increased plaque buildup in arteries leading to the brain (veröffentlicht 23.11.2022), American Heart Association
This article contains general advice only and should not be used for self-diagnosis or treatment. It cannot replace a doctor’s visit.