Early detection of diabetes: possible almost 20 years before the disease

  • Recognize diabetes early: Widespread disease could now be recognized early
  • Until 19 years before the disease thanks to biomarkers recognizable
  • Using the results The University of Tübingen is looking for an explanation

Almost six million people in Germany suffer from diabetes. Type 2 disease, which is triggered by the body’s increasing insulin resistance, is particularly common in Germany. According to the Federal Ministry of Health, around 90 to 95 percent of all diabetics are assigned to this type. According to Der Spiegel, diabetes is one of the most widespread diseases – but a research group from Sweden has made a promising discovery.

Detectable 19 years ahead – biomarkers as a warning light for diabetes?

In a study based on data from the 1993 “Malmö Diet and Cancer Study” involving a total of 5,318 people from Sweden and Finland, researchers came to an exciting conclusion. Because, according to the study, a “biomarker” could be identified that could indicate such a risk already 19 years before the onset of diabetes.

The supposed biomarker is the protein “follistatin”, which according to chemie.de can be found in all more developed animals. In humans, the protein originates mainly in the liver. When evaluating the study, the researchers found a link between the level of follistatin and the occurrence of diabetes.

“We found that higher levels of the circulating blood protein follistatin predicted type 2 diabetes up to 19 years before disease onset, independent of other known risk factors such as age, body mass index (BMI), fasting blood glucose, diet or physical activity,” says Dr. Yang De Marinis, professor at Lund University and lead author of the study, in a university press release.

Study results could prevent diabetes – early countermeasures possible

According to the authors, the effect can be explained using the results of the Tübingen study. These showed that follistatin promotes the breakdown of fat from adipose tissue. This in turn could contribute to higher lipid accumulation. This increases the risk of nonalcoholic fatty liver disease and type 2 diabetes, the news release states.

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In practice, this discovery could now help identify the risk of diabetes earlier and take decisive countermeasures.

In some cases, enough exercise and a healthy diet can be used to fight the disease in its early stages. Dr Yang de Marinis states that more research should be done in this direction.

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